The p38 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to MAPK14, and mitogen-activated protein kinase 14. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The p38 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing